报告时间:2026年10月19日(周一)下午 15:00-16:00
报告地点:苏州大学天赐庄校区精正楼103报告厅
报告人:金锁钦 教授,武汉大学
报告摘要:
Spatial omics technologies are transforming our ability to investigate the molecular architecture of tissues. However, moving from high-dimensional, noisy measurements to a coherent understanding of tissue organization, cellular communication, and cellular dynamics remains a fundamental challenge. Here, we present our recent efforts to develop deep learning approaches that integrate multimodal spatial omics data to enhance multi-view data representation, uncover biologically interpretable tissue architectures, and decode spatially resolved cell–cell communication networks that capture coordinated cellular interactions shaping tissue organization. Furthermore, we have developed a data-driven and mechanistic model–driven integrative framework to infer cellular dynamics, spatial patterns, and their signaling mechanisms within the tissue microenvironment.
报告人简介:
金锁钦,武汉大学数学与统计永利皇宫 教授,博士生导师,国家级青年人才。2016年博士毕业于武汉大学,师从邹秀芬教授,随后赴美国加州大学尔湾分校从事博士后研究,合作导师为聂青教授。主要从事数学、人工智能与生物医学交叉研究,在单细胞与空间组学数据的数学建模和算法开发、发展数学的理论与方法以解决生物医学前沿科学问题等方面开展了系列研究。以第一或通讯作者身份在Nature/Cell系列子刊(如 Nature Communications、Nature Neuroscience、Nature Protocols、Cell Genomics、Cell Reports)以及交叉学科一流期刊(如Genome Biology、Nucleic Acids Research)发表多篇高水平论文,合作论文发表在Nature、PNAS等期刊,并受邀在Nature Machine Intelligence等期刊发表前瞻性评述文章。其中细胞通讯工具CellChat累计他引1万余次,相关成果荣获2024年国际基础科学大会“前沿科学奖”。
邀请人:马欢飞